2,4(4,6) DERIVÉS DE PYRIMIDINE

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专利权人:

JANSSEN PHARMACEUTICA NV

发明人:

申请号：

EP05819148.7

公开号：

EP1824856B1

申请日:

2005.12.08

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention is drawn to 2,4 (4,6) pyrimidine derived macrocyclcs, pharmaceutical compositions thereof, and methods of making said compounds. The compounds disclosed herein are inhibitors of EGF receptor tyrosine kinases and are useful for treating cell proliferative disorders, including atherosclerosis, restenosis, and cancer.

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