Freyne, Eddy Jean Edgard,Embrechts, Werner Constant Johan,Emelen, Kristof van,Willems, Marc,Brandt, Sven Franciscus Anna van,Rombouts, Frederik Jan Rita
申请号:
NO20073492
公开号:
NO340130B1
申请日:
2007.07.09
申请国别(地区):
NO
年份:
2017
代理人:
摘要:
The present invention is drawn to 2,4 (4,6) pyrimidine derived macrocyclcs, pharmaceutical compositions thereof, and methods of making said compounds. The compounds disclosed herein are inhibitors of EGF receptor tyrosine kinases and are useful for treating cell proliferative disorders, including atherosclerosis, restenosis, and cancer.