FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA;ALMA MATER STUDIORUM - UNIVERSITA DI BOLOGNA
发明人:
DE VIVO, MARCO,SCARPELLI, RITA,CAVALLI, ANDREA,MIGLIORE, MARCO,PIOMELLI, DANIELE,HABRANT, DAMIEN,FAVIA, ANGELO
申请号：
CA2880436
公开号：
CA2880436A1
申请日:
2013.08.01
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The invention provides novel multitarget inhibitors of the enzymes Fatty Acid Amide Hydrolase (FAAH), Cyclooxygenase-1 (COX-1) and/or Cyclooxygenase-2 (COX-2) having a specific carbamate moiety on the meta or ortho position of the A ring of a substituted biphenyl core and having an halogen in the ortho position of the B ring of the biphenyl core. The invention concerns also with therapeutical application of the multitarget inhibitors in particular in the prevention and treatment of cancer.
