Fondazione Istituto Italiano di Tecnologia;Alma Mater Studiorum - Universita' Di Bologna;The Regents of the University of California;Alma Mater Studiorum - Universita Di Bologna
发明人:
De Vivo, Marco,Scarpelli, Rita,Cavalli, Andrea,Migliore, Marco,Piomelli, Daniele,Habrant, Damien,Favia, Angelo
申请号：
AU2013301626
公开号：
AU2013301626A1
申请日:
2013.08.01
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
The invention provides novel multitarget inhibitors of the enzymes Fatty Acid Amide Hydrolase (FAAH), Cyclooxygenase-1 (COX-1) and/or Cyclooxygenase-2 (COX-2) having a specific carbamate moiety on the meta or ortho position of the A ring of a substituted biphenyl core and having an halogen in the ortho position of the B ring of the biphenyl core. The invention concerns also with therapeutical application of the multitarget inhibitors in particular in the prevention and treatment of cancer.
