FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;ALMA MATER STUDIORUM—UNIVERSITA' DI BOLOGNA;THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
发明人:
Marco De Vivo,Rita Scarpelli,Andrea Cavalli,Marco Migliore,Daniele Piomelli,Damien Habrant,Angelo Favia
申请号：
US14420237
公开号：
US09630914B2
申请日:
2013.08.01
申请国别(地区):
US
年份:
2017
代理人:
摘要：
Multitarget inhibitors of the enzymes Fatty Acid Amide Hydrolase (FAAH), Cyclooxygenase-1 (COX-1) and/or Cyclooxygenase-2 (COX-2) having a specific carbamate moiety on the meta or ortho position of the A ring of a substituted biphenyl core and having an halogen in the ortho position of the B ring of the biphenyl core. Also concerns the therapeutical application of the multitarget inhibitors, in particular, in the prevention and treatment of cancer.
