Fondazione Istituto Italiano Di Tecnologia;Alma Mater Studiorum -Università di Bologna;The Regents of the University of California
发明人:
申请号:
EP13755978.7
公开号:
EP2880015B1
申请日:
2013.08.01
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
Multitarget inhibitors of the enzymes Fatty Acid Amide Hydrolase (FAAH), Cyclooxygenase-1 (COX-1) and/or Cyclooxygenase-2 (COX-2) having a specific carbamate moiety on the meta or ortho position of the A ring of a substituted biphenyl core and having an halogen in the ortho position of the B ring of the biphenyl core. Also concerns the therapeutical application of the multitarget inhibitors, in particular, in the prevention and treatment of cancer.