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Compositions of trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate(S)-3'-methyl-2' -(pentanoyl{ 2 -(tetrazol-5-ylate)biphenyl-4'-ylmethyl} amino)butyrate]hemipentahydrate
专利权人:
NOVARTIS AG
发明人:
AL-FAYOUMI, SULIMAN,HU, JIAHUI,KUMARAPERUMAL, NATRAJAN,ROYCE, ALAN, EDWARD,RUEGGER, COLLEEN,ZANNOU, ERIKA, AINA
申请号:
NZ58468608
公开号:
NZ584686A
申请日:
2008.11.04
申请国别(地区):
NZ
年份:
2013
代理人:
摘要:
584686 Disclosed is a solid oral dosage form that delivers a therapeutically effective amount of valsartan free acid, or a pharmaceutically acceptable salt thereof comprising: (a) a dual acting compound in a concentration from 4 percent to 90 percent by weight of the composition; and (b) at least one pharmaceutically acceptable excipient, wherein the dual acting compound is trisodium [3-((1S,3R)-1-biphenyl-4-yl methyl-3-ethoxycarbonyl-1-butylcarbamoyl) propionate-(S)-3'-methyl-2'-(pentanoyl{ 2 -(tetrazol-5-ylate)biphenyl-4'-ylmethyl} amino )butyrate]hemipentahydrate, wherein the dual acting compound is present in an amount of 40, 50, 100, 200 or 400 mg per unit dose.
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