CRYSTALLINE FORMS OF TRISODIUM SUPRAMOLECULAR COMPLEX COMPRISING VALSARTAN AND AHU-377 AND METHODS THEREOF

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专利权人:

Crystal Pharmatech Co.; Ltd.

发明人:

CHEN, Minhua,ZHANG, Yanfeng,YANG, Chaohui,ZHANG, Xiaoyu,LI, Jiaoyang,WANG, Peng,LI, Pixu

申请号：

EP15843405

公开号：

EP3229799A4

申请日:

2015.12.08

申请国别(地区):

EP

年份:

2017

代理人:

摘要：

Novel crystalline Forms of trisodium [3-((1S,3R)-1-biphenyl-4-ylmethyl-3-ethoxycarbonyl-1-butyl carbamoyl) propionate-(S)-3′-methyl-T-(pentanoyl{2″-(tetrazol-5-ylate)biphenyl-4′-ylmethyl}amino)butyrate] hydrate, methods for their preparation, pharmaceutical compositions comprising these new forms, and use of them for treating or delaying progression or onset of diseases or disorders related to activity of angiotensin receptor 1 (AT1) blockage and neprilysin (NEP) inhibition, such as heart failure, are disclosed.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/