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Comprimés à friabilité améliorée
专利权人:
Tower Laboratories; Ltd.
发明人:
申请号:
EP14165457.4
公开号:
EP2796131A1
申请日:
2014.04.22
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
Tablets are prepared with friability reducing agents to yield tablets that are more resistant to breakage or crumbling, but with satisfactory hardness. The friability reducing agents include low molecular weight polyethylene glycol as well as similar agents exhibiting at least three percent (3%) hydroxide moieties and a water solubility of at least eighty percent (80%) (w/w %) in room temperature water. The tablets may comprise an active agent and excipient of almost any type, and about 0.1 - about 0.5% by weight friability reducing agent. They exhibit a hardness of at least eighty percent (80%) of the same tablet prepared without the friability reducing agent.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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