Approach is provided for a high molecular weight polymeric composition and a new usage of the high-molecular weight polymeric composition. The new usage of the high-molecular weight polymeric composition directly adsorbs body fluid, or indirectly adsorbs toxin or stimulating substance existed in the intaked solution or liquid and removes the body fluid or the toxin or stimulating substance out of body. Therefore, the high-molecular weight polymeric composition is helpful to reduce the food digestibility or to prevent the toxin or stimulating substance from adsorbing in the gastrointestinal tract, even to bring the toxin or stimulating substance out of the body. Accordingly, the high-molecular weight polymeric composition is able to be applied to control weight by lowering the food digestibility or avoid damage by decreasing the toxin or stimulating substance released into the body. The high molecular weight polymeric composition has well biocompatibility to be widely applied in human.
