Xiaoxing Lv,Xin Yi,Meiru Zhao,Yanfang Guan,Tao Liu,Ling Yang
申请号：
US15751722
公开号：
US20180371453A1
申请日:
2016.02.18
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The present invention provides a low-frequency mutation enrichment sequencing method for free target DNA in plasma, comprising plasma DNA extraction and library construction, general library TT COLD PCR amplification enrichment, probe enrichment capture, PCR and sequencing of captured products, and positive and negatice double-strand error-correction low-frequency information analysis.
