Disclosed herein are compounds of formula(I) that may be specific to PPAR and/or EGF receptors,and methods of making and using same, whereinX is C1-C3alkylene, optionally substituted with one,two or three substituents selected from halogen orhydroxyl； R1 is selected from the group consisting ofC1--C6alkyl, C3-C6cycloalkyl, C2-C6alkenyl, andC2--C6alkynyl； R2 is selected from the group consisting ofhydrogen and C1-C6alkyl； R3 is independently selected,for each occurrence from the group consisting of hydrogen,C1-C6alkoxy, C1-C6alkyl, cyano, C3-C6cycloalkyl,halogen, hydroxyl, and nitro； R4 is selected from thegroup consisting of hydrogen and C1-C6alkyl； R5 is hydrogenC1-C6alkyl； or pharmaceutically acceptable saltsor N-oxides thereof.
