Disclosed herein are compounds of for¬mula (I) that may be specific to PPAR and/or EGF re¬ceptors, and methods of making and using same, where¬in X is C1-C3alkylene, optionally substituted with one, two or three substituents selected from halogen or hy-droxyl R1 is selected from the group consisting of C1-C6alkyl, C3-C6cycloalkyl, C2-C6alkenyl, and C2-C6alkynl R2 is selected from the group consisting of hydrogen and C1-C6alkyl R5 is independently selected, for each occurrence from the group consisting of hydro¬gen, C1-C6alkoxy, C1-C6alkyl, cyano, C3-C6cycloalkyl, halogen, hydroxyl, and nitro R4 is selected from the group consisting of hydrogen and C1-C6alkyl R5 is hy¬drogen C1-C6alkyl or pharmaceutically acceptable salts or N-oxides thereof