SIDDIQUI, M. ARSHAD,DAI, CHAOYANG,MANSOOR, UMAR FARUK,YANG, LIPING,VITHARANA, LALALNTHI DILRUKSHI,ANGELES, ANGIE R.
申请号:
CA2702922
公开号:
CA2702922C
申请日:
2008.10.16
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates tocompounds of Formula (I), below, (wherein X, R1, R2,R3, p, E, ring A, and ring B are as defined herein). Thepresent invention also relates to compositions (includingpharmaceutically acceptable compositions) comprisingthese compounds, alone and in combination with one ormore additional therapeutic agents, and to methods fortheir use in inhibiting KSP kinesin activity, and for treatingcellular proliferative diseases or disorders associated withKSP kinesin activity. Formula I [Chemical formula shouldbe inserted here as it appears on abstract in paper form.]