Lalalnthi Dilrukshi Vitharana;M. Arshad Siddiqui;Umar Faruk Mansoor;Liping Yang;Chaoyang Dai;Angie R. Angeles
发明人:
M. Arshad Siddiqui,Chaoyang Dai,Umar Faruk Mansoor,Liping Yang,Lalalnthi Dilrukshi Vitharana,Angie R. Angeles
申请号:
US12738537
公开号:
US08796460B2
申请日:
2008.10.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. Formula I