M. ARSHAD SIDDIQUI,CHAOYANG DAI,UMAR FARUK MANSOOR,LIPING YANG,LALANTHI DILRUKSHI VITHARANA,ANGIE R. ANGELES
申请号:
BRPI0818605
公开号:
BRPI0818605A2
申请日:
2008.10.16
申请国别(地区):
BR
年份:
2015
代理人:
摘要:
The present invention relates to compounds of Formula (I), below, (wherein X, R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present invention also relates to compositions (including pharmaceutically acceptable compositions) comprising these compounds, alone and in combination with one or more additional therapeutic agents, and to methods for their use in inhibiting KSP kinesin activity, and for treating cellular proliferative diseases or disorders associated with KSP kinesin activity. Formula I