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Spiro-condensed 1, 3, 4-thiadiazole derivatives for inhibiting KSP kinesin activity
专利权人:
Merck Sharp & Dohme Corp.
发明人:
Mansoor, Umar Faruk,Vitharana, Lalalnthi Dilrukshi,Siddiqui, M. Arshad,Yang, Liping,Dai, Chaoyang,Angeles, Angie R.
申请号:
AU2008312401
公开号:
AU2008312401C1
申请日:
2008.10.16
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention relates to compounds of Formula (I), below, (wherein X,R1, R2, R3, p, E, ring A, and ring B are as defined herein). The present inventionalso relates to compositions (including pharmaceutically acceptable compositions)comprising these compounds, alone and in combination with one or more additionaltherapeutic agents, and to methods for their use in inhibiting KSP kinesin activity,and for treating cellular proliferative diseases or disorders associated withKSP kinesin activity. Formula I [Chemical formula should be inserted here asit appears on abstract in paper form.]
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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