THE BROAD INSTITUTE, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人:
ZHANG, FENG,GOOTENBERG, JONATHAN,COX, DAVID BENJAMIN TURITZ,ABUDAYYEH, OMAR,KANNAN, SOUMYA
申请号:
CA3064601
公开号:
CA3064601A1
申请日:
2018.06.26
申请国别(地区):
CA
年份:
2019
代理人:
摘要:
The invention provides for systems, methods, and compositions for targetingand editing nucleic acids. In particular, theinvention provides non-naturally occurring or engineered RNA-targeting systemscomprising a RNA-targeting Cas13 protein, at leastone guide molecule, and at least one adenosine deaminase protein or catalyticdomain thereof.