THE BROAD INSTITUTE, INC.;PRESIDENT AND FELLOWS OF HARVARD COLLEGE;MASSACHUSETTS INSTITUTE OF TECHNOLOGY
发明人:
ZHANG, FENG,GOOTENBERG, JONATHAN,COX, DAVID BENJAMIN TURITZ,ABUDAYYEH, OMAR,KANNAN, SOUMYA
申请号：
CA3073848
公开号：
CA3073848A1
申请日:
2018.09.21
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The disclosure provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Casl3 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.
