The Broad Institute, Inc.;President and Fellows of Harvard College;Massachusetts Institute of Technology
发明人:
Zhang, Feng,Gootenberg, Jonathan,Cox, David Benjamin Turitz,Abudayyeh, Omar,Kannan, Soumya
申请号:
AU2020202810
公开号:
AU2020202810A1
申请日:
2020.04.29
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
#$%^&*AU2020202810A120200521.pdf#####ABSTRACT The disclosure provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.