The Broad Institute, Inc.;President and Fellows of Harvard College;Massachusetts Institute of Technology
发明人:
ZHANG, Feng,GOOTENBERG, Jonathan,COX, David Benjamin Turitz,ABUDAYYEH, Omar,KANNAN, Soumya
申请号:
AU2018290843
公开号:
AU2018290843A1
申请日:
2018.06.26
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The invention provides for systems, methods, and compositions for targeting and editing nucleic acids. In particular, the invention provides non-naturally occurring or engineered RNA-targeting systems comprising a RNA-targeting Cas13 protein, at least one guide molecule, and at least one adenosine deaminase protein or catalytic domain thereof.