The invention relates to novel substituted tetrahydro-4H-thieno-pyrrolo[3,2-c]pyridines of general formula 1, geometric isomers thereof, mixtures of the geometric isomers thereof, and pharmaceutically acceptable salts thereof, where Th is an annulated thiene ring； W is a single bond (in this case R3 is bonded directly to the nitrogen atom of the pyrrole ring), a methylene, 1,2-ethane, 1,2-ethylene, 1,2-acetylene, 1,3-propane or 1,3-allyl bridge optionally substituted by a hydroxyl group； R1 and R2 are hydrogen, C1-C4alkyl, halogen or -??2??； R3 is hydrogen, optionally substituted phenyl, optionally substituted azaheteroaryl； R4 is C1-C4alkyl, ??2?2?5 or ??2?(??3)3； R5, R6, R7, independently of one another, are hydrogen or C1-C4alkyl, or R5 and R6 together form an ethylene bridge and R7 is a hydrogen atom, or R5 and R7 together form an ethylene bridge and R6 is a hydrogen atom； and also to the synthesis of novel chemical substances, novel physiologically active substances, "molecular instruments", a pharmaceutical composition, methods for producing same and a method for treating and preventing the development of various diseases, including diseases of the central nervous system.
