CHO, SOON CHANGKR,조순장,KWON, JI WUNGKR,권지웅,SHIN, DAE KEUNKR,신대근,CHOI, HYE RANKR,최혜란,LEE, SU JUNGKR,이수정,CHAE, KYU SEOKR,채규서
申请号：
KR1020160151785
公开号：
KR1020180054171A
申请日:
2016.11.15
申请国别(地区):
KR
年份:
2018
代理人:
摘要：
The present invention relates to a method for extracting a compound for alleviating metabolic diseases from a raspberry unripe fruit. According to the present invention, a raspberry unripe fruit is extracted, and a raspberry extract is added with 70% ethanol, and is immersed at 60°C for 24 hours and filtered. Subsequently, filtered residue is extracted three times in the same method, and the obtained filtrate is concentrated under reduced pressure at 35°C, such that formula 1, NPK002B09A, which is an extract of 70% ethanol and a raspberry unripe fruit having a solvent completely removed therefrom, is obtained. Formula 2, NPK002B09C, is obtained by dissolving the extract of the formula 1 in 50% MeOH, adding hexane thereto three times, and distributing and concentrating the same. Formula 3, NPK002B09D, which is a raspberry unripe fruit fraction, is obtained by sequentially adding ethyl acetate and butanol thereto in the same method. Accordingly, a food composition which is a raspberry extract containing a compound of the formula, has an effect of inhibiting diabetes, obesity, and cholesterol.COPYRIGHT KIPO 2018본 발명은 복분자 미숙과를 추출한 후 상기 복분자 추출물에 70% 에탄올을 가하여 60℃에서 24시간 침지한 후 이를 필터 여과하였다. 여과 잔사를 동일한 방법으로 3회에 거처 추출하였으며, 얻어진 여액을 35℃에서 감압농축하여 용매가 완전히 제거된 복분자 미숙과 열매 70% 에탄올 추출물인 하기 구조식 1인 NPK002B09A을 얻었다. 이를 50% MeOH에 용해시킨 후 hexane을 3회 가하여 분배 농축하여 구조식 2인 NPK002B09C를 얻었다. 동일한 방법에 의해 순차적으로 ethyl acetate 및 butanol을 가하여 복분자 미숙과 분획물인 구조식 3인 NPK002B09D를 획특하였고 상기 구조식의 화합물을 함유하는 복분자 추출물인 식품조성물은 당뇨나, 비만, 콜레스톨의 억제 등에 효과가 있다.
