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TESTOSTERONE COMPOSITIONS
专利权人:
Ферринг Б.В. (NL)
发明人:
ГРЕНЬЕ Арно (FR),КАРРАРА Дарио Н. (CH)
申请号:
RU2013133082/15
公开号:
RU2013133082A
申请日:
2012.01.18
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A transdermal or transmucosal composition comprising: - 2% by weight, testosterone, - C-alkanol, - polyalcohol and monoalkyl ether of diethylene glycol, where the composition is essentially free of long chain fatty alcohols, long chain fatty acids and long chain fatty esters acids. 2. A transdermal or transmucosal composition according to claim 1, further comprising at least one of: a gelling agent, a neutralizing agent, a chelating agent and a solvent or any combination thereof. The composition of claim 1, wherein the alkanol is present in an amount of about 5-50 wt.%, The polyalcohol is present in an amount of about 1-30 wt.%, The penetration enhancer is present in an amount of about 0.2-25 wt.%, The gelling agent is present in in an amount of about 0.05-4 wt.%, a neutralizing agent is present in an amount of about 0.05-1 wt.%, and a chelating agent is present in an amount of about 0.001-5.0 wt.% 4. The composition of claim 1, wherein the alkanol is selected from one or more of the group consisting of ethanol, isopropanol and n-propanol. The composition of claim 1, wherein the alkanol is ethanol. The composition of claim 1, wherein the alkanol is ethanol, present in an amount of about 44.0 wt.%. The composition of claim 1, wherein the polyalcohol is propylene glycol. The composition of claim 1, wherein the polyalcohol is propylene glycol present in an amount of about 20.0 wt.%. The composition of claim 1, wherein one or both of diethylene glycol monoethyl ether and diethylene glycol monomethyl ether is present (s). The composition according to claim 1, wherein diethylene glycol monoethyl ether is present in an amount of 5.0% by weight.1. Трансдермальная или трансмукозальная композиция, содержащая:- 2% масс, тестостерона,- C-Cалканол,- полиспирт и- моноалкиловый эфир диэтиленгликоля,где указанная композиция, по существу, не содержит длинноцепочечных жирных спиртов, длинноцепочечных жирных кислот и длинноцепочечных сложных эфиров жирных кислот.2. Трансдермальная
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