MANSOUR, MARC,ORS, FREDERIC,STANFORD, MARIANNE,SAMMATUR, LEELADHAR,RAJAGOPALAN, RAJKANNAN,MACDONALD, LISA DIANA
申请号:
CA3038155
公开号:
CA3038155A1
申请日:
2016.09.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present disclosure provides methods, uses and compositions and kits for use in inducing an antibody immune response in a human subject. The methods and uses involve administering parenterally a low dose volume of a composition comprising an antigen comprising a B-cell epitope, an amphipathic compound, and a hydrophobic carrier, wherein the low dose volume of the composition is less than 100 µl and induces an antibody immune response to the B-cell epitope in the human subject.