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Methods of Using Low Dose Volume B-cell Epitope Compositions for Inducing an Antibody Immune Response in Human Subjects
专利权人:
IMMUNOVACCINE TECHNOLOGIES INC.
发明人:
Marc Mansour,Frederic Ors,Marianne Stanford,Leeladhar SAMMATUR,Rajkannan Rajagopalan,Lisa Diana MACDONALD
申请号:
US16336162
公开号:
US20190224312A1
申请日:
2016.09.27
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The present disclosure provides methods, uses and compositions and kits for use in inducing an antibody immune response in a human subject. The methods and uses involve administering parenterally a low dose volume of a composition comprising an antigen comprising a B-cell epitope, an amphipathic compound, and a hydrophobic carrier, wherein the low dose volume of the composition is less than 100 μl and induces an antibody immune response to the B-cell epitope in the human subject.
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