GUDAS JEAN,JAKOBOVITS AYA,JIA XIAO CHI,MORRISON ROBERT KENDALL,MORRISON KAREN JANE MEYRICK,SHAO HUI,CHALLITA EID PIA M,RAITANO ARTHUR B
申请号：
IN3189/DELNP/2011
公开号：
IN2011DN03189A
申请日:
2011.04.29
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
Antibodies and molecules derived therefrom that bind to novel PSCA protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response antibodies or T cells reactive with PSCA can be used in active or passive immunization.
