Pia M. Challita-Eid;Arthur B. Raitano;Aya Jakobovits;Wangmao Ge
发明人:
Wangmao Ge,Pia M. Challita-Eid,Arthur B. Raitano,Aya Jakobovits
申请号：
US12561832
公开号：
US08853364B2
申请日:
2009.09.17
申请国别(地区):
US
年份:
2014
代理人:
摘要：
PSCA and its encoded protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response； antibodies or T cells reactive with PSCA can be used in active or passive immunization.
