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Prostate stem cell antigen (PSCA) variants and sub-sequences thereof
专利权人:
AGENSYS; INC.
发明人:
GE, WANGMAO,JAKOBOVITS, AYA,RAITANO, ARTHUR B.
申请号:
DK11152953
公开号:
DK2319524T3
申请日:
2004.05.28
申请国别(地区):
DK
年份:
2013
代理人:
摘要:
PSCA and its encoded protein, and variants thereof, are described wherein PSCA exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, PSCA provides a diagnostic, prognostic, propylactic and/or therapeutic target for cancer. The PSCA gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with PSCA can be used in active or passive immunization.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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