Biopolymer-based matrices are an important basis for many cosmetic products or medical devices, such as implants, wound dressings or facial masks. It is therefore essential that the properties of the matrices are adaptable to the intended use. The present invention relates to a method for the production of a biocompatible matrix with adaptable properties the method comprising: a) providing a composition comprising at least one biopolymer； b) extruding the composition into a layer through a slit onto a surface, wherein the slit moves over the surface； c) freezing the composition after extrusion； d) optionally repeating the process to add one or more further layers； e) lyophilizing the frozen composition； f) optionally subjecting the composition to mechanical force. g) crosslinking the at least one biopolymer； wherein preferably the surface can be cooled. The invention further relates to a biocompatible matrix obtainable by the method as well as to the use of a matrix obtainable by the method for medical or cosmetic purposes.以生物高分子為基底之基質係許多化妝產品或醫療裝置之重要基體，如移植體、傷口敷料或面膜。因此基質性質必須對於預期用途具有適配性特性。本發明係關於一種製造具有適配性特性的生物相容基質的方法，所述方法包含： a) 提供包含至少一生物高分子的組成物； b) 透過狹縫擠製組成物至表面上以形成層體，其中狹縫在表面上方移動； c) 在擠製後冷凍組成物； d) 可選地重複上述步驟，以進一步增加一或多層層體； e) 凍乾被冷凍的組成物； f) 可選地對組成物施予機械力；以及 g) 交聯所述之至少一生物高分子， 其中較佳地該表面係可被冷卻的。 本發明係進一步關於由本發明之方法製得的生物相容基質以及由本發明之方法製得的基質用於醫藥或化妝品目的的用途。
