The present invention addresses the problem of developing a liposome composition having an excellent long-lasting skin moisturizing effect, excellent long-lasting skin tenseness and excellent long-lasting liposome stability. Provided is a liposome composition comprising the following components (a) to (e): (a) a phospholipid; (b) a Tremella Fuciformis extract; (c) vitamin E or a derivative thereof; (d) a polyhydric alcohol having an IOB value of 1.5 to 5; and (e) water.本發明係以開發一種保濕效果的持續性及緊緻感的持續性優良,甚而脂質體的歷時穩定性優異的脂質體組成物為課題。本發明係提供一種脂質體組成物,其係含有以下成分(a)~(e):(a)磷脂質、(b)銀耳萃取物、(c)維生素E或其衍生物、(d)IOB值1.5~5的多元醇、(e)水。