JASON ARNOLD LOTVIN,BRIAN BAHLER,TSU-SHUN LEE,MARK EDWARD RUPPEN,PAMELA SUE FINK CHARBONNEAU
申请号：
PT06740302
公开号：
PT1866342T
申请日:
2006.03.31
申请国别(地区):
PT
年份:
2019
代理人:
摘要：
A process for reducing the protein content and preserving the capsular polysaccharide content in a complex cellular Streptococcus pneumoniae lysate broth prior to purification is described. Utilizing pH reduction after cellular lysis has resulted in a purified polysaccharide that consistently meets the protein specification, and higher recovery yields of polysaccharide during the purification process.
