BAHLER Brian,LEE Tsu-shun,LOTVIN Jason Arnold,RUPPEN Mark Edward,CHARBONNEAU Pamela Sue Fink
申请号：
SI200632381
公开号：
SI3466982T1
申请日:
2006.03.31
申请国别(地区):
SI
年份:
2020
代理人:
摘要：
A process for reducing the protein content and preserving the capsular polysaccharide content in a complex cellular Streptococcus pneumoniae lysate broth prior to purification is described. Utilizing pH reduction after cellular lysis has resulted in a purified polysaccharide that consistently meets the protein specification, and higher recovery yields of polysaccharide during the purification process.
