PROBLEM TO BE SOLVED: To provide a pharmaceutical composition having an excellent cell proliferation suppressing activity.SOLUTION: The pharmaceutical composition for preventing or treating cancers comprises a thiazolidinedione compound or the like represented by general formula (I) [wherein Ar is an aryl group (which may be substituted with an NR1R2 group) R1 and R2 are same or different and they are each a hydrogen atom, a 1-6C alkyl group or the like X is an oxygen atom or a sulfur atom Y is a CH group or a nitrogen atom] and an RXR activating agent or the like as active ingredients.COPYRIGHT: (C)2003,JPO【課題】優れた細胞増殖抑制活性を有する医薬組成物を提供する。【解決手段】下記一般式(I)【化1】[式中、Arは、アリール基(-NR1R2基で置換)等、R1及びR2は、それぞれ同一又は異なって、水素原子、C1-6アルキル基等、Xは、酸素原子又は硫黄原子を示し、Yは、=CH-基又は窒素原子を示す。]で表されるチアゾリジンジオン化合物等及びRXR活性化作用剤等を有効成分として含有する、癌を予防又は治療するための医薬組成物。
