PROBLEM TO BE SOLVED: To microcapsulate efficiently a solid substance by a method wherein a substance forming an intermediate layer is separated in a phase from a liquid dispersion consisting of a solution containing the substance forming the intermediate layer and a solid substance difficult to be dissolved in the solution, and then a condensed polymerizable monomer is allowed to react in the dispersion liquid.SOLUTION: In the case where water is used as a solvent, a dispersion liquid comprising an aqueous solution containing a substance forming an intermediate layer, and a solid substance insoluble or difficult to be dissolved in the aqueous solution is adjusted. An aimed microcapsule is obtained by allowing a condensed polymerizable monomer to react in the diapersion liquid wherein the substance forming the intermediate layer is separated in a phase from the dispersion liquid aqueous solution. For the microcapsule, a macromolecular layer is formed on a layer comprising a substance forming the intermediate layer to be generally formed on the solid substance. Such a macromolecule is obtained by polymerizing a corresponding condensed polymerizable monomer in appropriate reacting conditions. Thereby, a solid substance of a medical active component, a pesticide active component, an aromatic component, etc., can be efficiently microcapsulated.COPYRIGHT: (C)1999,JPO【課題】 医薬活性成分、農薬活性成分、香料成分等である固体物質を効率的にマイクロカプセル化する方法及び優れた該固体物質のマイクロカプセル組成物を提供する。【解決手段】 中間層を形成する物質を含む溶液および該溶液に不溶または難溶な固体物質からなる分散液から中間層を形成する物質を相分離させ、次いで該中間層を形成する物質が相分離した分散液中で縮合重合性モノマーを反応させることを特徴とする固体物質のマイクロカプセル化方法等及び、かかる方法により得られるマイクロカプセル組成物。
