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CRYSTAL OF 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE HYDRATE, CRYSTAL OF 5-HYDROXY-1H-IMIDAZOLE-4-CARBOXAMIDE 3/4 HYDRATE, AND METHOD FOR PRODUCING SAME
专利权人:
FUJIFILM CORPORATION
发明人:
FUJIMOTO, TAISUKE,HASHIMOTO, TOMOHIRO,HAYASHI, KATSUYUKI,TANAKA, TOMOYUKI
申请号:
EP12835728
公开号:
EP2762469A4
申请日:
2012.09.28
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
Provided is a method for producing 5-hydroxy-1H-imidazole-4-carboxamide·3/4 hydrate, including: reacting 2-aminomalonamide with a compound represented by the following formula [1] in the presence of a carboxylic acid to obtain 5-hydroxy-1H-imidazole-4-carboxamide: wherein, in formula [1], each R independently represents a C 1-3 alkyl group reacting the resulting 5-hydroxy-1H-imidazole-4-carboxamide with an acidic compound to obtain a 5-hydroxy-1H-imidazole-4-carboxamide acid salt or a hydrate thereof and reacting the resulting 5-hydroxy-1H-imidazole-4-carboxamide acid salt or hydrate thereof with a salt in the presence of an acidic solvent to obtain the 5-hydroxy-1H-imidazole-4-carboxamide·3/4 hydrate.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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