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Crystal of 5-hydroxy-1H-imidazole-4-carboxamide 3/4 hydrate, method for producing the same and crystal of 5-hydroxy-1H-imidazole-4-carboxamide hydrate
专利权人:
发明人:
Taisuke Fujimoto,Tomohiro Hashimoto,Katsuyuki Hayashi,Tomoyuki Tanaka
申请号:
US14226364
公开号:
US09108928B2
申请日:
2014.03.26
申请国别(地区):
US
年份:
2015
代理人:
摘要:
Provided is a method for producing 5-hydroxy-1H-imidazole-4-carboxamide.3/4 hydrate, including:reacting 2-aminomalonamide with a compound represented by the following formula [1] in the presence of a carboxylic acid to obtain 5-hydroxy-1H-imidazole-4-carboxamide:wherein, in formula [1], each R independently represents a C1-3 alkyl group reacting the resulting 5-hydroxy-1H-imidazole-4-carboxamide with an acidic compound to obtain a 5-hydroxy-1H-imidazole-4-carboxamide acid salt or a hydrate thereof and reacting the resulting 5-hydroxy-1H-imidazole-4-carboxamide acid salt or hydrate thereof with a salt in the presence of an acidic solvent to obtain the 5-hydroxy-1H-imidazole-4-carboxamide.3/4 hydrate.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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