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СПОСОБЫ ЛЕЧЕНИЯ И/ИЛИ ПОДАВЛЕНИЯ ПРИРОСТА МАССЫ
专利权人:
АНДОРЕШЕРШ; ИНК. (CA)
发明人:
ЛЯБРИ Фернан (CA),ДЕШЕЭ Ив (CA),РИШАР Дени (CA),МАРТЕЛЬ Селин (CA),МАРЕТТ Андре (CA)
申请号:
RU2013148518/15
公开号:
RU2013148518A
申请日:
2013.10.30
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method of treating or inhibiting the development of obesity comprising administering to a subject in need of such treatment or suppression, a therapeutically effective amount of a compound or a pharmaceutically acceptable salt thereof of the following general formula: wherein R independently are selected from the group consisting of hydrogen, hydroxyl, -OM (wherein M is selected from the group consisting of straight or branched C-alkyl, straight or branched C alkenyl, a straight or branched alkynyl-C) and portion convertible in vivo to hydroxyl, wherein G is -H or -CH and wherein Roboznachaet type of substituent selected from the group consisting of pyrrolidinyl, piperidino, morpholino, and NRaRb (wherein Ra and Rb are independently hydrogen, straight or branched-alkyl, straight- or branched-alkenyl and straight- or branched-alkynyl) where R or Rne is pivaloiloksigruppoy.2. A method according to Claim. 1, wherein said compound is optically active because it represents more than 50% of the stereoisomer having an absolute configuration S on carbon 2.3. A method according to claim. 2, wherein said compound or salt substantially excludes (2R) -enantiomer.4. A method according to Claim. 1, where the compound is acid salt selected from the group consisting of acetic acid, adipic acid, benzenesulfonic acid, benzoic acid, camphorsulfonic acid, citric acid, fumaric acid, hydroiodic acid, hydrobromic acid, hydrochloric acid, gidrohlortiazidinovoy acid, hydroxynaphthoic acid, lactic acid, maleic acid, methanesulfonic acid, methylsulfuric acid, 1,5-naphthalenedisulfonic
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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