Willow Diluzio,Phuong M. Nguyen,Csanad M. Varga,Vaithianathan Palaniappan,Jason Brown,Irving H. Fox,Catherine Scholz,Erica Helen Jenkins,Maria Rosario
申请号：
US16009865
公开号：
US20180346578A1
申请日:
2018.06.15
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Antibody formulations are described comprising a mixture of an anti-a4b7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-a4b7 antibody in vivo.
