Csanad M. Varga;Phoung M. Nguyen;Willow Diluzio;Vaithianathan Palaniappan;Jason Brown
发明人:
Willow Diluzio,Phoung M. Nguyen,Csanad M. Varga,Vaithianathan Palaniappan,Jason Brown
申请号：
US14114835
公开号：
US10040855B2
申请日:
2012.05.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
Antibody formulations are described comprising a mixture of an anti-α4β7 antibody, an antioxidant or chelator, and at least one free amino acid. The disclosed formulations may have improved stability, reduced aggregate formation, or both. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-α4β7 antibody in vivo.
