Ji Duck Kim,Hong-Chul Yoon,Seong Hee Cho,Inwoo Kim,Min Jae Cho,In Young Lee,Hyae Jung Hyun,Eunkyung Park
申请号：
US12934638
公开号：
US08362012B2
申请日:
2009.04.16
申请国别(地区):
US
年份:
2013
代理人:
摘要：
The present invention relates to a novel benzoxazine benzimidazole derivative of formula (1) as an antagonist against a vanilloid receptor-1, a pharmaceutical composition comprising the same as an active ingredient, and a use thereof. The benzoxazine benzimidazole derivative of the present invention may be useful for preventing or treating a disease associated with antagonistic activity of vanilloid receptor-1:wherein, R1, R2, R3, R3′, Q1, Q2, Q3 and Q4 have same meanings as defined in the specification.
