KIM, JI DUCK,YOON, HONG-CHUL,CHO, SEONG HEE,KIM, INWOO,CHO, MIN JAE,LEE, IN YOUNG,HYUN, HYAE JUNG,PARK, EUNKYUNG
申请号:
EP09733372
公开号:
EP2264031A4
申请日:
2009.04.16
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
The present invention relates to a novel benzoxazine benzimidazole derivative of formula (1) as an antagonist against a vanilloid receptor-1, a pharmaceutical composition comprising the same as an active ingredient, and a use thereof. The benzoxazine benzimidazole derivative of the present invention may be useful for preventing or treating a disease associated with antagonistic activity of vanilloid receptor-1:wherein, R1, R2, R3, R3, Q1, Q2, Q3 and Q4 have same meanings as defined in the specification.