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Naphthamides as anticancer agents
专利权人:
Xiangshu Xiao
发明人:
Xiangshu Xiao,Bingbing Li
申请号:
US13125289
公开号:
US08653086B2
申请日:
2009.10.21
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A compound (particularly useful for inhibiting cancer) according to formula I:or a pharmaceutically acceptable salt thereof, wherein: x is 0 or 1 R1-R6 are each independently H, —CN, —NO2, —NO, —OH, halogen, hydroxyalkyl, carboxyl, substituted carboxyl, aminocarbonyl, alkoxy, carbonyl or substituted carbonyl R7 is H, alkyl, alkyl amino, aminoacyl, hydroxyacyl, heteroaryl, heterocycloalkyl, alkyl heteroaryl or alkyl heterocycloalkyl R8 is H or alkyl A is O or N and Ar is an aryl, substituted aryl, heteroaryl, or substituted heteroaryl, provided that if R7 is H then Ar is aryl substituted with alkyl amino.
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