Disclosed are methods of treating disorders of the eye by administering to a patient in need of such treatment a compound represented by the formula Wherein R1 and R2 are independently hydrogen, alkyl, substituted alkyl, cycloalkyl, alkynyl, substituted alkynyl, cyano, alkoxy, carboxamido, substituted carboxamido, and if R1 and R2 are alkyl, R1 and R2 may be joined with a bond or &mdash(CH2)m&mdash to produce a cycloalkyl, R3 and R4 are independently hydrogen, alkyl, hydroxyl, alkoxy, cyano, fluoro, and if R3 and R4 are alkyl, R3 and R4 may be joined with a bond or &mdash(CH2)m&mdash to produce a cycloalkyl, Q may be absent, hydrogen, alkyl, cycloalkyl, cycloalkenyl, alkoxy, substituted alkoxy, substituted thio, cyano, thionitrile, sulfonamide, substituted sulfonamide, substituted sulfonyl, aromatic, substituted aromatic, heteroaromatic, substituted heteroaromatic, or bicycloheteroaromatic, R5 is hydrogen, alkyl, cycloalkyl, or when R6 is also alkyl, together with R6 may form a heterocycloalkyl ring, R6 may be hydrogen, alkyl, substituted alkyl, or &mdashOR7, R7 is alkyl or, when R5 is alkyl, together with R5 forms a 5-, 6-, or 7-membered ring, L may be &mdashO&mdash, &mdashS&mdash, &mdashN&boxH or absent, Z may be carbon or nitrogen or absent, m is 1, 2 or 3, n is 0, 1 or 2, and when n is 0, Q may be directly bonded to Z, or a pharmaceutically acceptable addition salt of an acid or base thereof.【課題】目の障害を処置するための方法を提供する。【解決手段】 処置の必要な患者に対して、請求項に定義された式(I)によって示される化合物、あるいはそれらの酸または塩基の薬学的に許容される付加塩を投与することによる。【選択図】 図1
