BLANCHETOT CHRISTOPHE,DE HAARD JOHANNES,DREIER TORSTEN,DE JONGE NATALIE,VAN DER WONING SEBASTIAN PAUL,ONGENAE NICOLAS
申请号:
IN9702/DELNP/2014
公开号:
IN2014DN09702A
申请日:
2014.11.17
申请国别(地区):
IN
年份:
2016
代理人:
摘要:
The present invention provides binding molecules (e.g. antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL 6 (e.g. human mouse and non human primate IL 6). In a preferred embodiment the antibodies or antigen binding fragments of the invention bind to IL 6 and inhibit its binding to an IL 6 receptor. Such antibodies or antigen binding fragments are particularly useful for treating IL 6 associated diseases or disorders (e.g. inflammatory disease and cancer).