Van Der Woning, Sebastian Paul,Ongenae, Nicolas,Blanchetot, Christophe,De Haard, Johannes,Dreier, Torsten,De Jonge, Natalie
申请号：
AU2013264779
公开号：
AU2013264779B2
申请日:
2013.05.23
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). In a preferred embodiment, the antibodies or antigen binding fragments of the invention bind to IL-6 and inhibit its binding to an IL-6 receptor. Such antibodies or antigen binding fragments are particularly useful for treating IL-6- associated diseases or disorders (e.g., inflammatory disease and cancer).
