Christophe BLANCHETOT,Johannes DE HAARD,Torsten DREIER,Natalie DE JONGE,Sebastian Paul VAN DER WONING,Nicolas ONGENAE
申请号：
US16239321
公开号：
US20190233509A1
申请日:
2019.01.03
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The present invention provides binding molecules (e.g., antibodies or antigen binding fragments thereof) that specifically bind to and inhibit the biological activity of IL-6 (e.g., human, mouse and non-human primate IL-6). In a preferred embodiment, the antibodies or antigen binding fragments of the invention bind to IL-6 and inhibit its binding to an IL-6 receptor. Such antibodies or antigen binding fragments are particularly useful for treating IL-6-associated diseases or disorders (e.g., inflammatory disease and cancer).
