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ОБОГАЩЕННЫЙ РУТИНОМ ЭКСТРАКТ И СПОСОБ ЕГО ПОЛУЧЕНИЯ
专利权人:
ЭйЭлПиЭс ФАРМАСЬЮТИКАЛЗ; ИНД. КО.; ЛТД. (JP)
发明人:
МИНАМИ Кадзунобу (JP),ТАНИВАКИ Синдзи (JP),КАЦУМАТА Акико (JP)
申请号:
RU2015119261
公开号:
RU2015119261A
申请日:
2012.10.22
申请国别(地区):
RU
年份:
2016
代理人:
摘要:
1. A process for preparing an extract enriched rutin, comprising: dissolving rutin-containing plant extract in methanol or ethanol to obtain a crude extract solution rutin, wherein said rutin-containing plant extract comprises 90% by weight - 95% by weight of rutin and 100-300 hours. The. / mn iron, reduction of volume of the crude extract routine to obtain a concentrate solution, forming a mixture by adding acid to the concentrate in an amount of 1-15% by weight relative to rutin-containing plant extract and optionally a C1-C4 alcohol, water. s or both of these components, wherein said rutin-containing plant extract is 8% -30% (w / v) of the total mixture and wherein said acid is selected from the group consisting of ascorbic acid, citric acid, tartaric acid, malic acid and gallic acid, incubating the mixture to form a precipitate iotdelenie precipitate, thereby obtaining a rich rutin extract, which contains less than 20 parts / million zheleza.2. A method according to Claim. 1, wherein rutin-containing plant extract is obtained as a crude precipitate based on extracts of Uncaria elliptica, Sophora Japonica or Fava danta water, alcohol or aqueous spirta.3. A method according to Claim. 1, where added and the C1-C4 alcohol, and vodu.4. A method according to Claim. 1, wherein the acid is added in an amount 1-10ves.% Relative to the total rutin-containing vegetable ekstrakta.5. A method according to claim. 4, wherein the acid is added in an amount of 1-5 wt.% Relative to the total rutin-containing vegetable ekstrakta.6. The method of claim. 5, wherein the acid is added in an amount of 2-4 wt.% Relative to the total rutin-containing vegetable ekstrakta.7. A method according to claim. 3, where the C1-C4 alcohol and water is added as an aqueous solution of a C1 -C4 alcohol which contains 5-80 vol.% Vody.8. A method according to claim. 3 wherein1. Способ получения обогащенного рутином экстракта, включающий:растворение рутин-содержащего растительного экстракта в метаноле ил
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