PROBLEM TO BE SOLVED: To provide a liposome composition, more specifically, one which has excellent storage stability due to inclusion of a ceramide in a liposome by non-crystallization and which can sufficiently exert barrier function improvement effect even inside a horny layer of rough skin due to percutaneous absorption of the liposome including the non-crystallized ceramide.SOLUTION: A liposome composition is characterized by containing the following components (A) to (D): (A) a ceramide (B) a dextrin fatty acid ester satisfying the following conditions (1) to (3): (1) the fatty acid has a substitution degree of 1.4 to 1.8 per glucose unit, (2) the fatty acid has a composition of (a) a straight chain saturated fatty acid having a carbon number of 12 to 22 and (b) a branch saturated fatty acid having a carbon number of 8 to 22, where the content molar ratio of (a) and (b) is 60:40 to 95:5, and (3) the glucose in the dextrin moiety has an average polymerization degree of 3 to 150 (C) phospholipid and (D) cholesterol or phytosterol.
