STABLE ANTI-TNFR1 POLYPEPTIDES, ANTIBODY VARIABLE DOMAINS AND ANTAGONISTS

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专利权人:

GLAXO GROUP LIMITED

发明人:

DE SILVA INUSHA,STOOP ADRIAAN ALLART,SEPP ARMIN

申请号：

ZA201203052

公开号：

ZA201203052B

申请日:

2012.04.25

申请国别(地区):

ZA

年份:

2013

代理人:

摘要：

The invention relates to storage-stable anti-TNFR1 antibody single variable domains (dAbs), antagonists and multispecific ligands, as well as methods and uses of these. The anti-TNFR1 polypeptides, antibody single variable domains (dAbs), antagonists and multispecific ligands are useful for treating and/or preventing inflammatory disease, such as arthritis or COPD, as well as for pulmonary administration, oral administration, delivery to the lung and delivery to the GI tract of a patient.

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